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Standards

Editorial policy

How clinical content on this site is sourced, written, reviewed and corrected.

Every clinical page here names its author, names its medical reviewer, and carries the date it was last checked. No page quotes a success rate or promises an outcome. When we get something wrong, we fix it in place and change the date.

What every clinical page must say

Four statements, on every page, without exception
  • Ketamine is a Schedule III controlled substance, legal to prescribe and legal to use off-label by any licensed prescriber.
  • Off-label does not mean unregulated, but it does mean no agency has reviewed the specific protocol a clinic is running.
  • There is no federal certification for an intravenous ketamine clinic, and no single national standard it must meet.
  • Esketamine is the exception: it can only be given at a REMS-certified centre with observation afterwards.

Off-label is legal and ordinary in psychiatry. It also means no regulator reviewed the protocol a clinic is running, and readers deserve to know which they are looking at.

What no page may do

The lines we will not cross

Signals worth slowing down for

  • A guaranteed result, or a published success rate with no study behind it.
  • No psychiatric assessment before the first infusion.
  • Pressure to buy a package of sessions before a single consultation has happened.
  • Vagueness about who is in the room and what their credential is.
  • Claims that the treatment works for a very long list of unrelated conditions.
  • No discussion of what happens when the effect fades.

Found an error?

Tell us and we will fix it

Corrections are made in place and the review date changes with them. Nothing is edited silently. Write to us and we would rather hear it from a reader than not at all.

Compare the full course, not the first session. That is where programmes actually differ.

This is general information, not medical advice. Ketamine is a controlled substance and its use for mood disorders is off-label, apart from esketamine. Talk to a clinician who knows your history. In the US, call or text 988 if you are in crisis.

Not medical advice Ketamine is a Schedule III controlled substance and its use for mood disorders is off-label, with the exception of esketamine, which is FDA-approved for treatment-resistant depression and restricted to certified centres. Nothing on this page can establish whether treatment suits you. That judgement belongs to a clinician who knows your history. In the United States, call or text 988 if you are in crisis.